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DNA Modifications Measured in Blood Signal Related Changes in the Brain

Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone — and showing signs of anxiety — are directly related to changes found in their brain tissues. The proof-of-concept study, reported online ahead of print in the June issue of Psychoneuroendocrinology, offers what the research team…

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Poverty 'Ages' Genes of Young Children Study Shows

The stress of growing up in a poor and unstable household affects children as young as 9 years old on a genetic level, shortening a portion of their chromosomes that scientists say is a key indicator of aging and illness, according to a study released Monday. The researchers say their findings are the first that document this type of genetic change…

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2014 | Christopher Kelty + Aaron Panofsky – Disentangling Public Participation in Science and Biomedicine

ISG faculty, Dr. Christopher Kelty and Dr. Aaron Panofsky, have published a paper titled “Disentangling Public Participation In Science and Biomedicine” in Genome Medicine. ABSTRACT: Background This article provides a framework for disentangling the concept of participation, with emphasis on participation in genomic medicine. We have derived seven ‘dimensions’ of participation that are most frequently invoked in the extensive, heterogeneous literature on participation.…

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Hummingbird Evolution Is Booming

Hummingbirds took just 22 million years to diversify from a single common ancestor into 338 tiny, colorful species. And they have not finished yet. Evolutionary biologist Jim McGuire of the University of California, Berkeley, and his collaborators have found that although some hummingbird groups have saturated the available space in their environments, others are still developing into new species at…

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CRISPR Reverses Disease Symptoms in Living Animals for First Time

MIT scientists report the use of a CRISPR methodology to cure mice of a rare liver disorder caused by a single genetic mutation. They say their study (“Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype”), published in Nature Biotechnology, offers the first evidence that this gene-editing technique can reverse disease symptoms in living animals. CRISPR, which provides a…

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