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Scythian Horse Breeding Unveiled: Lessons for Animal Domestication

Nomad Scythian herders roamed vast areas spanning the Central Asian steppes during the Iron Age, approximately from the 9th to the 1st century BCE (Before Common Era). These livestock pastoralists, who lived on wagons covered by tents, left their mark in the history of warfare for their exceptional equestrian skills. They were among the first to master mounted riding and…

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Study Finds First Molecular Genetic Evidence of PTSD Heritability

A large new study from the Psychiatric Genomics Consortium provides the first molecular genetic evidence that genetic influences play a role in the risk of getting Posttraumatic Stress Disorder (PTSD) after trauma. The report extends previous findings that showed that there is some shared genetic overlap between PTSD and other mental disorders such as schizophrenia. It also finds that genetic risk…

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Scientists Unveil CRISPR-based Diagnostic Platform

A team of scientists from the Broad Institute of MIT and Harvard, the McGovern Institute for Brain Research at MIT, the Institute for Medical Engineering & Science at MIT, and the Wyss Institute for Biologically Inspired Engineering at Harvard University has adapted a CRISPR protein that targets RNA (rather than DNA) as a rapid, inexpensive, highly sensitive diagnostic tool with the potential…

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“Smart” Cephalopods Trade Off Genome Evolution for Prolific RNA Editing

Octopus, squid, and cuttlefish are famous for engaging in complex behavior, from unlocking an aquarium tank and escaping to instantaneous skin camouflage to hide from predators. A new study suggests their evolutionary path to neural sophistication includes a novel mechanism: Prolific RNA editing at the expense of evolution in their genomic DNA. The study, led by Joshua J.C. Rosenthal of…

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Fish Study Shows Important Genome Interactions in Animal Cells

In a new study, researchers at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science examined how the interaction of two genomes in animal cells — the mitochondrial and nuclear genomes — interact to affect adaptation of the Atlantic killifish to different temperatures. They showed that although these genomes are separate physical entities, the mitochondrial genome affects…

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Blind Tadpoles Learn Visually After Researchers Graft Eyes Onto Tails And Treat Them With Neurotransmitter Drugs

Blind tadpoles were able to process visual information from eyes grafted onto their tails after being treated with a small molecule neurotransmitter drug that augmented innervation, integration, and function of the transplanted organs, according to a paper published online today by researchers at the Allen Discovery Center at Tufts University in npj Regenerative Medicine, a Nature Research journal. The work,…

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