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2014 | Christopher Kelty + Aaron Panofsky – Disentangling Public Participation in Science and Biomedicine

ISG faculty, Dr. Christopher Kelty and Dr. Aaron Panofsky, have published a paper titled “Disentangling Public Participation In Science and Biomedicine” in Genome Medicine. ABSTRACT: Background This article provides a framework for disentangling the concept of participation, with emphasis on participation in genomic medicine. We have derived seven ‘dimensions’ of participation that are most frequently invoked in the extensive, heterogeneous literature on participation.…

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Hummingbird Evolution Is Booming

Hummingbirds took just 22 million years to diversify from a single common ancestor into 338 tiny, colorful species. And they have not finished yet. Evolutionary biologist Jim McGuire of the University of California, Berkeley, and his collaborators have found that although some hummingbird groups have saturated the available space in their environments, others are still developing into new species at…

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CRISPR Reverses Disease Symptoms in Living Animals for First Time

MIT scientists report the use of a CRISPR methodology to cure mice of a rare liver disorder caused by a single genetic mutation. They say their study (“Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype”), published in Nature Biotechnology, offers the first evidence that this gene-editing technique can reverse disease symptoms in living animals. CRISPR, which provides a…

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Pesticides Make the Life of Earthworms Miserable

Pesticides have a direct impact on the physiology and behavior of earthworms, a Danish/French research team reports after having studied earthworms that were exposed to pesticides over generations. “We see that the worms have developed methods to detoxify themselves, so that they can live in soil sprayed with fungicide. They spend a lot of energy on detoxifying, and that comes…

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2014 | Eric Vilain, et.al – Mutant Cohesin in Premature Ovarian Failure

ISG Director, Eric Vilain, and his research team have published a paper titled “Mutant Cohesin in Premature Ovarian Failure” in the premier medical journal New England Journal of Medicine SUMMARY: Premature ovarian failure is a major cause of female infertility. The genetic causes of this disorder remain unknown in most patients. Using whole-exome sequence analysis of a large consanguineous family with inherited…

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