The genome of the Western lowland gorilla (Gorilla gorilla ssp. gorilla) has been sequenced at a high level of quality beginning to approach that of the human genome, says a team of scientists led by Prof. Evan Eichler from the University of Washington. Prof. Eichler and his colleagues used long-read sequencing technology, along with a unique combination of algorithms, to…
Dr. David Reich from Harvard Medical School and his colleagues have produced a world map of Denisovan and Neanderthal ancestry in 120 diverse populations. Their analysis proposes that Denisovan admixture into humans occurred about 100 generations after Neanderthal admixture. Dr. Reich and co-authors collected their data by comparing known Neanderthal and Denisovan gene sequences across more than 250 genomes from…
In a new evolutionary proof of the old adage, ‘we are what we eat’, Cornell University scientists have found tantalizing evidence that a vegetarian diet has led to a mutation that — if they stray from a balanced omega-6 to omega-3 diet — may make people more susceptible to inflammation, and by association, increased risk of heart disease and colon…
Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body. The findings will be presented as part of a poster presentation by members of the Rutgers…
Now that everyone who wants to sound sophisticated about health care is talking about “personalized medicine”—even the president!—the open question is, what part of medicine is going to get personalized first? Which is to say, what can the intricacies of people’s genomes say about the best way to treat what ails them? The answers may well be in blood. Why…
About eight percent of our DNA is viral in origin: remnants of ancient battles between infectious viruses and our ancestors. These so-called endogenous viruses are often perceived as a mere oddity with no clear biological significance. But a new study by scientists at the University of Utah School of Medicine shows that evolution has repurposed some of these viral remains into weapons…