In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute (TSRI) have elucidated how the virus attacks the brains of newborns, information that could accelerate the development of treatments. The study, led by TSRI Associate Professors Hyeryun Choe and Damon Page, was published…
Scientists have devised a powerful new tool for understanding how DNA controls gene activity in cells. The tool allows researchers to map at high resolution, across large swaths of a cell’s genome, which DNA nucleotides work to regulate gene activity. “This is the first method that enables us to simultaneously test thousands of human DNA regulatory regions for their ability…
There’s no need to reinvent the genetic wheel. That’s one lesson of a new study that looks to the saliva of humans, gorillas, orangutans, macaques and African green monkeys for insights into evolution. The research, published on Aug. 25 in Scientific Reports, examined a gene called MUC7 that tells the body how to create a salivary protein of the same…
Scientists say they are closer to pinning down the genetic causes of inherited diseases ranging from muscular dystrophy to certain types of heart disease after analysing the DNA of more than 60,000 people. Researchers have discovered more than 3,000 genes in which certain mutations are likely to play a role in disease, as well as more than 160 genetic mutations…
Conducting the first large-scale, genome-wide analyses of ancient human remains from the Near East, an international team led by Harvard Medical School has illuminated the genetic identities and population dynamics of the world’s first farmers. The study reveals three genetically distinct farming populations living in the Near East at the dawn of agriculture 12,000 to 8,000 years ago: two newly…
A federal biosafety and ethics panel on Tuesday unanimously approved the first study in patients of the genome-editing technology CRISPR/Cas9, in an experiment that would use CRISPR to create genetically-altered immune cells to attack three kinds of cancer. The experiment, proposed by scientists at the University of Pennsylvania, still needs the approval of the medical centers where it would be…