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Searching Big Data Faster

For more than a decade, gene sequencers have been improving more rapidly than the computers required to make sense of their outputs. Searching for DNA sequences in existing genomic databases can already take hours, and the problem is likely to get worse. Recently, Bonnie Berger’s group at MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) has been investigating techniques to…

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Editing Humanity

The genome is written in an alphabet of just four letters. Being able to read, study and compare DNA sequences for humans, and thousands of other species, has become routine. A new technology promises to make it possible to edit genetic information quickly and cheaply. This could correct terrible genetic defects that blight lives. It also heralds the distant prospect…

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The Biological Origins of Sexual Orientation and Gender Identity

Male? Female? The distinction is not always clear. Exploring the scientific evidence for the biological origins of sexual orientation and gender identity must continue to both enhance patient care and fight discrimination. People often are unaware of the biological complexity of sex and gender, says Eric Vilain, MD (RES ’98, FEL ’99), PhD, director of the Center for Gender-Based Biology…

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Cellphone Data Can Track Infectious Diseases

Tracking mobile phone data is often associated with privacy issues, but these vast datasets could be the key to understanding how infectious diseases are spread seasonally, according to a study published in the Proceedings of the National Academy of Sciences. Princeton University and Harvard University researchers used anonymous mobile phone records for more than 15 million people to track the…

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