In a provocative new perspective piece, Stanford researchers say that disease genes are spread uniformly across the genome, not clustered in specific molecular pathways, as has been thought. The gene activity of cells is so broadly networked that virtually any gene can influence disease, the researchers found. As a result, most of the heritability of diseases is due not to…
Nomad Scythian herders roamed vast areas spanning the Central Asian steppes during the Iron Age, approximately from the 9th to the 1st century BCE (Before Common Era). These livestock pastoralists, who lived on wagons covered by tents, left their mark in the history of warfare for their exceptional equestrian skills. They were among the first to master mounted riding and…
A team spanning Baylor College of Medicine, Rice University, Texas Children’s Hospital and the Broad Institute of MIT and Harvard has developed a new way to sequence genomes, which can assemble the genome of an organism, entirely from scratch, dramatically cheaper and faster. While there is much excitement about the so-called “$1000 genome” in medicine, when a doctor orders the…
Male pregnancy. A long, tube-shaped mouth with no teeth. A body covered with bony plates. These are the odd, quintessential features of seahorses, but why? Scientists dove into this question on Wednesday by publishing the first complete sequence of a seahorse genome. “We have discovered an array of changes in the genome, which helps to explain why the seahorse looks…
Small enough to fit into the palm of your hand, with enormous eyes and an appetite for meat, tarsiers are an anomaly of nature. They are also our distant cousins, according to scientists at Washington University School of Medicine in St. Louis, who recently sequenced and analyzed the tarsier genome. The findings, published Oct. 6 in Nature Communications, place tarsiers on…
Scientists say they are closer to pinning down the genetic causes of inherited diseases ranging from muscular dystrophy to certain types of heart disease after analysing the DNA of more than 60,000 people. Researchers have discovered more than 3,000 genes in which certain mutations are likely to play a role in disease, as well as more than 160 genetic mutations…