2025
Landecker, Hannah
Life as Aftermath: Social Theory for an Age of Anthropogenic Biology Journal Article
In: Science, Technology, & Human Values, vol. 50, no. 4, pp. 679–712, 2025, ISSN: 1552-8251.
@article{Landecker2024,
title = {Life as Aftermath: Social Theory for an Age of Anthropogenic Biology},
author = {Hannah Landecker},
doi = {10.1177/01622439241233946},
issn = {1552-8251},
year = {2025},
date = {2025-07-00},
journal = {Science, Technology, & Human Values},
volume = {50},
number = {4},
pages = {679--712},
publisher = {SAGE Publications},
abstract = {Anthropogenic pressures now shape the development, interrelations, and evolution of microbes, plants, animals, and humans. In an age of oxidative stress and failures of DNA repair, cytokine storms and microbial dysbiosis, social scientific theory stutters in the face of biological consequences of forces it masterfully detailed, from biopower to looping kinds. Concepts of the fallibility of knowledge from the unanticipated consequence to the wicked problem are too generic to fathom the nature of the living within reconfigured biotic-abiotic relations in the aftermath of industrialization. Working through examples—genetic modification in weed control, and solvents in cryobiology—this paper offers a novel analytic for anthropogenic biology specific to the relations between knowledge and life in the wake of the industrial twentieth century: a novel patterning of living matter and process from the molecular to the ecological arising with forms of biological control. Changes in pathogens and hosts, targets and bystanders are specific to the form of control but not anticipated by it, illegible within its originating logics. Hubris gone moldy, anthropogenic biology grows from forms of power that overestimate the comprehensiveness of their own efficacy, mistaking the ability to temporarily control living things for full knowledge of them. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2024
Tornini, Valerie A; Fernandez, Robert W; Goldman, Olivia V; Suarez, Joanne
DEI infrastructures required for the best science and medicine Journal Article
In: The Lancet, vol. 403, no. 10442, 2024, ISSN: 0140-6736.
@article{Tornini2024,
title = {DEI infrastructures required for the best science and medicine},
author = {Valerie A Tornini and Robert W Fernandez and Olivia V Goldman and Joanne Suarez},
doi = {10.1016/s0140-6736(24)00697-4},
issn = {0140-6736},
year = {2024},
date = {2024-06-00},
journal = {The Lancet},
volume = {403},
number = {10442},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Bezanson, Michelle; Cortés-Ortiz, Liliana; Bicca-Marques, Júlio César; Boonratana, Ramesh; Carvalho, Susana; Cords, Marina; de la Torre, Stella; Hobaiter, Catherine; Humle, Tatyana; Izar, Patrícia; Lynch, Jessica W.; Matsuzawa, Tetsuro; Setchell, Joanna M.; Zikusoka, Gladys Kalema; Strier, Karen B.
News and Perspectives: Words matter in primatology Journal Article
In: Primates, vol. 65, no. 1, pp. 33–39, 2024, ISSN: 1610-7365.
@article{Bezanson2023,
title = {News and Perspectives: Words matter in primatology},
author = {Michelle Bezanson and Liliana Cortés-Ortiz and Júlio César Bicca-Marques and Ramesh Boonratana and Susana Carvalho and Marina Cords and Stella de la Torre and Catherine Hobaiter and Tatyana Humle and Patrícia Izar and Jessica W. Lynch and Tetsuro Matsuzawa and Joanna M. Setchell and Gladys Kalema Zikusoka and Karen B. Strier},
doi = {10.1007/s10329-023-01104-6},
issn = {1610-7365},
year = {2024},
date = {2024-01-00},
journal = {Primates},
volume = {65},
number = {1},
pages = {33--39},
publisher = {Springer Science and Business Media LLC},
abstract = {Abstract Postings on social media on Twitter (now X), BioAnthropology News (Facebook), and other venues, as well as recent publications in prominent journals, show that primatologists, ecologists, and other researchers are questioning the terms “Old World” and “New World” due to their colonial implications and history. The terms are offensive if they result in erasing Indigenous voices and history, ignoring the fact that Indigenous peoples were in the Americas long before European colonization. Language use is not without context, but alternative terminology is not always obvious and available. In this perspective, we share opinions expressed by an international group of primatologists who considered questions about the use of these terms, whether primatologists should adjust language use, and how to move forward. The diversity of opinions provides insight into how conventional terms used in primatological research and conservation may impact our effectiveness in these domains. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2023
Garrison, Nanibaa' A.; Carroll, Stephanie Russo
Genetic research with Indigenous Peoples: perspectives on governance and oversight in the US Journal Article
In: Front. Res. Metr. Anal., vol. 8, 2023, ISSN: 2504-0537.
@article{Garrison2023,
title = {Genetic research with Indigenous Peoples: perspectives on governance and oversight in the US},
author = {Nanibaa' A. Garrison and Stephanie Russo Carroll},
doi = {10.3389/frma.2023.1286948},
issn = {2504-0537},
year = {2023},
date = {2023-11-22},
journal = {Front. Res. Metr. Anal.},
volume = {8},
publisher = {Frontiers Media SA},
abstract = {Introduction Indigenous Peoples are increasingly exerting governance and oversight over genomic research with citizens of their nations, raising questions about how best to enforce research regulation between American Indian, Alaska Native, and Native Hawaiian peoples and researchers. Methods Using a community-engaged research approach, we conducted 42 semi-structured interviews with Tribal leaders, clinicians, researchers, policy makers, and Tribal research review board members about their perspectives on ethical issues related to genetics research with Indigenous Peoples in the US. Results We report findings related to (1) considerations for Indigenous governance, (2) institutional relationships upholding sovereignty, (3) expectations for research approvals, and (4) agreements enacting Indigenous governance. Participants described concerns about different ways of exerting oversight, relationships and agreements between Indigenous Peoples and researchers, and gaps that need to be addressed to strengthen existing governance of genomic data. Discussion The results will ultimately guide policy-making and development of new strategies for Indigenous Peoples to enforce oversight in research to promote ethically and culturally appropriate research. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Landecker, Hannah
Enzyme Power Journal Article
In: vol. 122, no. 847, pp. 283–288, 2023, ISSN: 1944-785X.
@article{Landecker2023b,
title = {Enzyme Power},
author = {Hannah Landecker},
doi = {10.1525/curh.2023.122.847.283},
issn = {1944-785X},
year = {2023},
date = {2023-11-01},
volume = {122},
number = {847},
pages = {283--288},
publisher = {University of California Press},
abstract = {Thanks to scientific discoveries and commercial efforts to harness the processes of fermentation going back to the nineteenth century, enzymes harvested from microbes have become ubiquitous in detergents and other cleaning products, as well as in food production. They are also now being adapted for an even bigger cleaning task: remediating pollution. Examining how these humble proteins and the biochemical reactions they catalyze became so indispensable reveals a little-noticed history of industrialization underlying modern everyday life. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Landecker, Hannah L.; Clark, Amander T.
Human embryo models made from pluripotent stem cells are not synthetic; they aren’t embryos, either Journal Article
In: Cell Stem Cell, vol. 30, no. 10, pp. 1290–1293, 2023, ISSN: 1934-5909.
@article{Landecker2023,
title = {Human embryo models made from pluripotent stem cells are not synthetic; they aren’t embryos, either},
author = {Hannah L. Landecker and Amander T. Clark},
doi = {10.1016/j.stem.2023.09.006},
issn = {1934-5909},
year = {2023},
date = {2023-10-00},
journal = {Cell Stem Cell},
volume = {30},
number = {10},
pages = {1290--1293},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Martins, Amely Branquinho; Valença-Montenegro, Mônica Mafra; Lima, Marcela Guimarães Moreira; Lynch, Jessica W.; Svoboda, Walfrido Kühl; de Sousa e Silva-Júnior, José; Röhe, Fábio; Boubli, Jean Philippe; Fiore, Anthony Di
In: Genes, vol. 14, no. 5, 2023, ISSN: 2073-4425.
@article{Martins2023,
title = {A New Assessment of Robust Capuchin Monkey (Sapajus) Evolutionary History Using Genome-Wide SNP Marker Data and a Bayesian Approach to Species Delimitation},
author = {Amely Branquinho Martins and Mônica Mafra Valença-Montenegro and Marcela Guimarães Moreira Lima and Jessica W. Lynch and Walfrido Kühl Svoboda and José de Sousa e Silva-Júnior and Fábio Röhe and Jean Philippe Boubli and Anthony Di Fiore},
doi = {10.3390/genes14050970},
issn = {2073-4425},
year = {2023},
date = {2023-05-00},
journal = {Genes},
volume = {14},
number = {5},
publisher = {MDPI AG},
abstract = {Robust capuchin monkeys, Sapajus genus, are among the most phenotypically diverse and widespread groups of primates in South America, with one of the most confusing and often shifting taxonomies. We used a ddRADseq approach to generate genome-wide SNP markers for 171 individuals from all putative extant species of Sapajus to access their evolutionary history. Using maximum likelihood, multispecies coalescent phylogenetic inference, and a Bayes Factor method to test for alternative hypotheses of species delimitation, we inferred the phylogenetic history of the Sapajus radiation, evaluating the number of discrete species supported. Our results support the recognition of three species from the Atlantic Forest south of the São Francisco River, with these species being the first splits in the robust capuchin radiation. Our results were congruent in recovering the Pantanal and Amazonian Sapajus as structured into three monophyletic clades, though new morphological assessments are necessary, as the Amazonian clades do not agree with previous morphology-based taxonomic distributions. Phylogenetic reconstructions for Sapajus occurring in the Cerrado, Caatinga, and northeastern Atlantic Forest were less congruent with morphology-based phylogenetic reconstructions, as the bearded capuchin was recovered as a paraphyletic clade, with samples from the Caatinga biome being either a monophyletic clade or nested with the blond capuchin monkey. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Shapiro, Nicholas; James, Jackie; Barry, Liz; Crawford, Shaun; Pusatier, Jennifer; Henderson, Adele; Logsdon, Timothy; Hogenkamp, Joyce; Gentile, Tom
Refining Relationships: How an Unlikely Community–Scientist Partnership Led to a Historic Environmental Justice Victory Journal Article
In: Environmental Justice, vol. 16, no. 2, pp. 151–161, 2023, ISSN: 1937-5174.
@article{Shapiro2023,
title = {Refining Relationships: How an Unlikely Community–Scientist Partnership Led to a Historic Environmental Justice Victory},
author = {Nicholas Shapiro and Jackie James and Liz Barry and Shaun Crawford and Jennifer Pusatier and Adele Henderson and Timothy Logsdon and Joyce Hogenkamp and Tom Gentile},
doi = {10.1089/env.2022.0018},
issn = {1937-5174},
year = {2023},
date = {2023-04-01},
journal = {Environmental Justice},
volume = {16},
number = {2},
pages = {151--161},
publisher = {Mary Ann Liebert Inc},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Martschenko, Daphne Oluwaseun; Callier, Shawneequa L.; Garrison, Nanibaa’ A.; Lee, Sandra Soo‐Jin; Turley, Patrick; Meyer, Michelle N.; Parens, Erik
Wrestling with Public Input on an Ethical Analysis of Scientific Research Journal Article
In: Hastings Center Report, vol. 53, no. S1, 2023, ISSN: 1552-146X.
@article{Martschenko2023,
title = {Wrestling with Public Input on an Ethical Analysis of Scientific Research},
author = {Daphne Oluwaseun Martschenko and Shawneequa L. Callier and Nanibaa’ A. Garrison and Sandra Soo‐Jin Lee and Patrick Turley and Michelle N. Meyer and Erik Parens},
doi = {10.1002/hast.1478},
issn = {1552-146X},
year = {2023},
date = {2023-03-00},
journal = {Hastings Center Report},
volume = {53},
number = {S1},
publisher = {Wiley},
abstract = {Abstract Bioethicists frequently call for empirical researchers to engage participants and community members in their research, but don't themselves typically engage community members in their normative research. In this article, we describe an effort to include members of the public in normative discussions about the risks, potential benefits, and ethical responsibilities of social and behavioral genomics (SBG) research. We reflect on what might—and might not— be gained from engaging the public in normative scholarship and on lessons learned about public perspectives on the risks and potential benefits of SBG research and the responsible conduct and communication of such research. We also provide procedural lessons for others in bioethics who are interested in engaging members of the public in their research . },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Meyer, Michelle N.; Appelbaum, Paul S.; Benjamin, Daniel J.; Callier, Shawneequa L.; Comfort, Nathaniel; Conley, Dalton; Freese, Jeremy; Garrison, Nanibaa' A.; Hammonds, Evelynn M.; Harden, K. Paige; Lee, Sandra Soo‐Jin; Martin, Alicia R.; Martschenko, Daphne Oluwaseun; Neale, Benjamin M.; Palmer, Rohan H. C.; Tabery, James; Turkheimer, Eric; Turley, Patrick; Parens, Erik
Wrestling with Social and Behavioral Genomics: Risks, Potential Benefits, and Ethical Responsibility Journal Article
In: Hastings Center Report, vol. 53, no. S1, 2023, ISSN: 1552-146X.
@article{Meyer2023,
title = {Wrestling with Social and Behavioral Genomics: Risks, Potential Benefits, and Ethical Responsibility},
author = {Michelle N. Meyer and Paul S. Appelbaum and Daniel J. Benjamin and Shawneequa L. Callier and Nathaniel Comfort and Dalton Conley and Jeremy Freese and Nanibaa' A. Garrison and Evelynn M. Hammonds and K. Paige Harden and Sandra Soo‐Jin Lee and Alicia R. Martin and Daphne Oluwaseun Martschenko and Benjamin M. Neale and Rohan H. C. Palmer and James Tabery and Eric Turkheimer and Patrick Turley and Erik Parens},
doi = {10.1002/hast.1477},
issn = {1552-146X},
year = {2023},
date = {2023-03-00},
journal = {Hastings Center Report},
volume = {53},
number = {S1},
publisher = {Wiley},
abstract = {Abstract In this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often‐ugly history of scientific attempts to understand the genetic contributions to human behaviors and social outcomes. They then describe what the current science—including genomewide association studies and polygenic indexes—can and cannot tell us, as well as its risks and potential benefits. They conclude with a discussion of responsible behavior in the context of SBG research. SBG research that compares individuals within a group according to a “sensitive” phenotype requires extra attention to responsible conduct and to responsible communication about the research and its findings. SBG research (1) on sensitive phenotypes that (2) compares two or more groups defined by (a) race, (b) ethnicity, or (c) genetic ancestry (where genetic ancestry could easily be misunderstood as race or ethnicity) requires a compelling justification to be conducted, funded, or published. All authors agree that this justification at least requires a convincing argument that a study's design could yield scientifically valid results; some authors would additionally require the study to have a socially favorable risk‐benefit profile . },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
França, Ephraim A.; dos Santos Machado Pereira, Felipe; Lorenzo, Mariana Pauletti; Lynch, Jessica W.; Orsi, Mário Luis; Vidotto-Magnoni, Ana Paula
Same-sex and immature sexual behaviour repertoire in a wild group of robust capuchin monkeys Journal Article
In: Folia Primatol., vol. 94, no. 2-3, pp. 129–145, 2023, ISSN: 1421-9980.
@article{França2023,
title = {Same-sex and immature sexual behaviour repertoire in a wild group of robust capuchin monkeys},
author = {Ephraim A. França and Felipe dos Santos Machado Pereira and Mariana Pauletti Lorenzo and Jessica W. Lynch and Mário Luis Orsi and Ana Paula Vidotto-Magnoni},
doi = {10.1163/14219980-bja10009},
issn = {1421-9980},
year = {2023},
date = {2023-02-15},
journal = {Folia Primatol.},
volume = {94},
number = {2-3},
pages = {129--145},
publisher = {Walter de Gruyter GmbH},
abstract = {Abstract
In primates, same-sex and immature sexual behaviour is widespread and can include mounting and genital presentation. These patterns can be observed in multiple social contexts and across all ages, and can serve functions such as appeasement, reconciliation, practice and dominance assertion. In this study, we investigated same-sex and immature sexual behaviour in a group of robust capuchins (Sapajus nigritus ) living in an Atlantic forest fragment and urban areas. We predicted that in order to practice sex, sexual behaviour in same-sex dyads and/or dyads that included immatures would resemble the adult heterosexual repertoire for solicitation through courtship displays, mounts and post-copulatory display. We also predicted that immature individuals would engage more frequently than adults in sexual interactions, in order to practice sex. We conducted all-occurrence observations of sexual behaviour in the study group (28 individuals: four adult males, one sub-adult male, eight adult females, eight juveniles and seven infants) from September 2016 to August 2017. Sexual interactions that included at least one immature individual in the dyad and/or occurred between individuals of the same sex were infrequent (N = 52, 0.13 interactions/hour), but much more frequent than heterosexual sexual interactions between adults in the group (N = 4, 0.01 interactions/hour). The same-sex and immature sexual repertoire resembled the described heterosexual patterns for the same species from the literature. Individuals displayed solicitation behaviours in “one-way courtship”, usually followed by a two-way courtship and then mounts, but post-copulatory behaviour was never observed. Except for the alpha male, all age-sex classes engaged in sexual interactions in same-sex dyads or in dyads that included immature individuals. We found no difference in frequency of participation across age classes, however, male-male dyads engaged more frequently in sexual interactions and may be practicing sex and courtship behaviours. Mounts are unlikely to be a form of dominance assertion as the alpha male did not participate, subordinate adult males did not engage in mounts with other subordinate adult males, juveniles mounted adult males and vice versa , and there were mount switches (taking turns as mounter and mountee) regardless of the initial mounter’s age. Contrary to the post-conflict context observed in Cebus , most mounts in this study were preceded by play. Combining our study with additional evidence for the genus, same-sex mounts and mounts that include immatures seem to occur most commonly in affiliative contexts within Sapajus . Sexual behaviour functions in Sapajus require additional investigation, especially among adult males and juveniles of both sexes. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Transgenerational inheritance and its modulation by environmental cues Book Chapter
In: Current Topics in Developmental Biology, pp. 31–76, Elsevier, 2023, ISBN: 9780128201572.
@inbook{2023,
title = {Transgenerational inheritance and its modulation by environmental cues},
doi = {10.1016/bs.ctdb.2022.10.002},
isbn = {9780128201572},
year = {2023},
date = {2023-00-00},
booktitle = {Current Topics in Developmental Biology},
pages = {31--76},
publisher = {Elsevier},
keywords = {},
pubstate = {published},
tppubtype = {inbook}
}
2022
Steinberg, Danielle L.; Lynch, Jessica W.; Cartmill, Erica A.
A robust tool kit: First report of tool use in captive crested capuchin monkeys (Sapajus robustus) Journal Article
In: American J Primatol, vol. 84, no. 11, 2022, ISSN: 1098-2345.
@article{Steinberg2022,
title = {A robust tool kit: First report of tool use in captive crested capuchin monkeys (\textit{Sapajus robustus})},
author = {Danielle L. Steinberg and Jessica W. Lynch and Erica A. Cartmill},
doi = {10.1002/ajp.23428},
issn = {1098-2345},
year = {2022},
date = {2022-11-00},
journal = {American J Primatol},
volume = {84},
number = {11},
publisher = {Wiley},
abstract = {Abstract Primate tool use is of great interest but has been reported only in a limited number of species. Here we report tool use in crested capuchin monkeys (Sapajus robustus ), an almost completely unstudied robust capuchin species. Crested capuchins and their sister species, the yellow‐breasted capuchin, diverged from a common ancestor over 2 million years ago, so this study fills a significant gap in understanding of tool use capacity and variation within the robust capuchin monkey radiation. Our study group was a captive population of seven individuals at the Santa Ana Zoo in California. The monkeys were given no prior training, and they were provided with a variety of enrichment items, including materials that could be used as tools as well as hard‐to‐access resources, for open‐ended interactions. In 54 observation hours, monkeys performed eleven tool use actions: digging, hammering, probing, raking, sponging, striking, sweeping, throwing, waving, wedging, and wiping. We observed tool modification, serial tool use, and social learning opportunities, including monkeys' direct observation of tool use and tolerated scrounging of foods obtained through tool use. We also observed significant individual skew in tool use frequency, with one individual using tools daily, and two individuals never using tools during the study. While crested capuchins have never been reported to use tools in the wild, our findings provide evidence for the species' capacity and propensity for tool use, highlighting the urgent need for research on this understudied, endangered primate. By providing detailed data on clearly identified S. robustus individuals, this study marks an effort to counteract the overgeneralization in the captive literature in referring to any robust capuchins of unknown provenance or ancestry as Cebus apella , a practice that obfuscates potential differences among species in tool use performance and repertoire in one of the only species‐rich tool‐using genera in the world. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lewis, Anna C. F.; Molina, Santiago J.; Appelbaum, Paul S.; Dauda, Bege; Rienzo, Anna Di; Fuentes, Agustin; Fullerton, Stephanie M.; Garrison, Nanibaa’ A.; Ghosh, Nayanika; Hammonds, Evelynn M.; Jones, David S.; Kenny, Eimear E.; Kraft, Peter; Lee, Sandra S. -J.; Mauro, Madelyn; Novembre, John; Panofsky, Aaron; Sohail, Mashaal; Neale, Benjamin M.; Allen, Danielle S.
Getting genetic ancestry right for science and society Journal Article
In: Science, vol. 376, no. 6590, pp. 250–252, 2022, ISSN: 1095-9203.
@article{Lewis2022,
title = {Getting genetic ancestry right for science and society},
author = {Anna C. F. Lewis and Santiago J. Molina and Paul S. Appelbaum and Bege Dauda and Anna Di Rienzo and Agustin Fuentes and Stephanie M. Fullerton and Nanibaa’ A. Garrison and Nayanika Ghosh and Evelynn M. Hammonds and David S. Jones and Eimear E. Kenny and Peter Kraft and Sandra S.-J. Lee and Madelyn Mauro and John Novembre and Aaron Panofsky and Mashaal Sohail and Benjamin M. Neale and Danielle S. Allen},
doi = {10.1126/science.abm7530},
issn = {1095-9203},
year = {2022},
date = {2022-04-15},
journal = {Science},
volume = {376},
number = {6590},
pages = {250--252},
publisher = {American Association for the Advancement of Science (AAAS)},
abstract = {We must embrace a multidimensional, continuous view of ancestry and move away from continental ancestry categories },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Carroll, Stephanie Russo; Garba, Ibrahim; Plevel, Rebecca; Small-Rodriguez, Desi; Hiratsuka, Vanessa Y.; Hudson, Maui; Garrison, Nanibaa’ A.
Using Indigenous Standards to Implement the CARE Principles: Setting Expectations through Tribal Research Codes Journal Article
In: Front. Genet., vol. 13, 2022, ISSN: 1664-8021.
@article{Carroll2022,
title = {Using Indigenous Standards to Implement the CARE Principles: Setting Expectations through Tribal Research Codes},
author = {Stephanie Russo Carroll and Ibrahim Garba and Rebecca Plevel and Desi Small-Rodriguez and Vanessa Y. Hiratsuka and Maui Hudson and Nanibaa’ A. Garrison},
doi = {10.3389/fgene.2022.823309},
issn = {1664-8021},
year = {2022},
date = {2022-03-21},
journal = {Front. Genet.},
volume = {13},
publisher = {Frontiers Media SA},
abstract = {Biomedical data are now organized in large-scale databases allowing researchers worldwide to access and utilize the data for new projects. As new technologies generate even larger amounts of data, data governance and data management are becoming pressing challenges. The FAIR principles (Findable, Accessible, Interoperable, and Reusable) were developed to facilitate data sharing. However, the Indigenous Data Sovereignty movement advocates for greater Indigenous control and oversight in order to share data on Indigenous Peoples’ terms. This is especially true in the context of genetic research where Indigenous Peoples historically have been unethically exploited in the name of science. This article outlines the relationship between sovereignty and ethics in the context of data to describe the collective rights that Indigenous Peoples assert to increase control over their biomedical data. Then drawing on the CARE Principles for Indigenous Data Governance (Collective benefit, Authority to control, Responsibility, and Ethics), we explore how standards already set by Native nations in the United States, such as tribal research codes, provide direction for implementation of the CARE Principles to complement FAIR. A broader approach to policy and procedure regarding tribal participation in biomedical research is required and we make recommendations for tribes, institutions, and ethical practice. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Goff, Anne Le; Louvel, Séverine; Boullier, Henri; Allard, Patrick
Toxicoepigenetics for Risk Assessment: Bridging the Gap Between Basic and Regulatory Science Journal Article
In: Genet Epigenet, vol. 15, 2022, ISSN: 2516-8657.
@article{LeGoff2022,
title = {Toxicoepigenetics for Risk Assessment: Bridging the Gap Between Basic and Regulatory Science},
author = {Anne Le Goff and Séverine Louvel and Henri Boullier and Patrick Allard},
doi = {10.1177/25168657221113149},
issn = {2516-8657},
year = {2022},
date = {2022-01-00},
journal = {Genet Epigenet},
volume = {15},
publisher = {SAGE Publications},
abstract = { Toxicoepigenetics examines the health effects of environmental exposure associated with, or mediated by, changes in the epigenome. Despite high expectations, toxicoepigenomic data and methods have yet to become significantly utilized in chemical risk assessment. This article draws on a social science framework to highlight hitherto overlooked structural barriers to the incorporation of toxicoepigenetics in risk assessment and to propose ways forward. The present barriers stem not only from the lack of maturity of the field but also from differences in constraints and standards between the data produced by toxicoepigenetics and the regulatory science data that risk assessment processes require. Criteria and strategies that frame the validation of knowledge used for regulatory purposes limit the application of basic research in toxicoepigenetics toward risk assessment. First, the need in regulatory toxicology for standardized methods that form a consensus between regulatory agencies, basic research, and the industry conflicts with the wealth of heterogeneous data in toxicoepigenetics. Second, molecular epigenetic data do not readily translate into typical toxicological endpoints. Third, toxicoepigenetics investigates new forms of toxicity, in particular low-dose and long-term effects, that do not align well with the traditional framework of regulatory toxicology. We propose that increasing the usefulness of epigenetic data for risk assessment will require deliberate efforts on the part of the toxicoepigenetics community in 4 areas: fostering the understanding of epigenetics among risk assessors, developing knowledge infrastructure to demonstrate applicability, facilitating the normalization and exchange of data, and opening the field to other stakeholders. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2021
Campbell-Staton, Shane C.; Walker, Reena H.; Rogers, Savannah A.; León, Jason De; Landecker, Hannah; Porter, Warren; Mathewson, Paul D.; Long, Ryan A.
Physiological costs of undocumented human migration across the southern United States border Journal Article
In: Science, vol. 374, no. 6574, pp. 1496–1500, 2021, ISSN: 1095-9203.
@article{Campbell-Staton2021,
title = {Physiological costs of undocumented human migration across the southern United States border},
author = {Shane C. Campbell-Staton and Reena H. Walker and Savannah A. Rogers and Jason De León and Hannah Landecker and Warren Porter and Paul D. Mathewson and Ryan A. Long},
doi = {10.1126/science.abh1924},
issn = {1095-9203},
year = {2021},
date = {2021-12-17},
journal = {Science},
volume = {374},
number = {6574},
pages = {1496--1500},
publisher = {American Association for the Advancement of Science (AAAS)},
abstract = {Dangerous terrain
As climate change leads to regions of the world becoming increasingly uninhabitable, unregulated human migration is likely to increase. Migrants often traverse dangerous terrain, and the environmental conditions they encounter when exposed can be deadly. Campbell-Staton
et al
. used an approach commonly used to predict spatially explicit regions of physiological challenge in animal species to create a hazard landscape for the border crossing between the United States and Mexico. Their predictions of high risk, particularly due to dehydration, coincided with regions of high migrant mortality. Such detailed predictions may help to prevent these tragedies. —SNV
},
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As climate change leads to regions of the world becoming increasingly uninhabitable, unregulated human migration is likely to increase. Migrants often traverse dangerous terrain, and the environmental conditions they encounter when exposed can be deadly. Campbell-Staton
. used an approach commonly used to predict spatially explicit regions of physiological challenge in animal species to create a hazard landscape for the border crossing between the United States and Mexico. Their predictions of high risk, particularly due to dehydration, coincided with regions of high migrant mortality. Such detailed predictions may help to prevent these tragedies. —SNV
Carson, Savanna L.; Casillas, Alejandra; Castellon-Lopez, Yelba; Mansfield, Lisa N.; Morris, D’Ann; Barron, Juan; Ntekume, Ejiro; Landovitz, Raphael; Vassar, Stefanie D.; Norris, Keith C.; Dubinett, Steven M.; Garrison, Nanibaa’ A.; Brown, Arleen F.
COVID-19 Vaccine Decision-making Factors in Racial and Ethnic Minority Communities in Los Angeles, California Journal Article
In: JAMA Netw Open, vol. 4, no. 9, 2021, ISSN: 2574-3805.
@article{Carson2021,
title = {COVID-19 Vaccine Decision-making Factors in Racial and Ethnic Minority Communities in Los Angeles, California},
author = {Savanna L. Carson and Alejandra Casillas and Yelba Castellon-Lopez and Lisa N. Mansfield and D’Ann Morris and Juan Barron and Ejiro Ntekume and Raphael Landovitz and Stefanie D. Vassar and Keith C. Norris and Steven M. Dubinett and Nanibaa’ A. Garrison and Arleen F. Brown},
doi = {10.1001/jamanetworkopen.2021.27582},
issn = {2574-3805},
year = {2021},
date = {2021-09-01},
journal = {JAMA Netw Open},
volume = {4},
number = {9},
publisher = {American Medical Association (AMA)},
abstract = {Importance The COVID-19 pandemic has had disproportionate effects on racial and ethnic minority communities, where preexisting clinical and social conditions amplify health and social disparities. Many of these communities report lower vaccine confidence and lower receipt of the COVID-19 vaccine. Understanding factors that influence the multifaceted decision-making process for vaccine uptake is critical for narrowing COVID-19–related disparities. Objective To examine factors that members of multiethnic communities at high risk for COVID-19 infection and morbidity report as contributing to vaccine decision-making. Design, Setting, and Participants This qualitative study used community-engaged methods to conduct virtual focus groups from November 16, 2020, to January 28, 2021, with Los Angeles County residents. Potential participants were recruited through email, video, and telephone outreach to community partner networks. Focus groups were stratified by self-identified race and ethnicity as well as age. Transcripts were analyzed using reflexive thematic analysis. Main Outcomes and Measures Themes were categorized by contextual, individual, and vaccine-specific influences using the World Health Organization’s Vaccine Hesitancy Matrix categories. Results A total of 13 focus groups were conducted with 70 participants (50 [71.4%] female) who self-identified as American Indian (n = 17 [24.3%]), Black/African American (n = 17 [24.3%]), Filipino/Filipina (n = 11 [15.7%]), Latino/Latina (n = 15 [21.4%]), or Pacific Islander (n = 10 [14.3%]). A total of 39 participants (55.7%) were residents from high-poverty zip codes, and 34 (48.6%) were essential workers. The resulting themes included policy implications for equitable vaccine distribution: contextual influences (unclear and unreliable information, concern for inequitable access or differential treatment, references to mistrust from unethical research studies, accessibility and accommodation barriers, eligibility uncertainty, and fears of politicization or pharmaceutical industry influence); social and group influences (inadequate exposure to trusted messengers or information, altruistic motivations, medical mistrust, and desire for autonomy); and vaccination-specific influences (need for vaccine evidence by subpopulation, misconceptions on vaccine development, allocation ambiguity, vaccination safety preferences, the importance of perceiving vaccine equity, burden of vaccine scheduling, cost uncertainty, and desire for practitioner recommendation). Conclusions and Relevance In this qualitative study, participants reported a number of factors that affected their vaccine decision-making, including concern for inequitable vaccine access. Participants endorsed policy recommendations and strategies to promote vaccine confidence. These results suggest that support of informed deliberation and attainment of vaccine equity will require multifaceted, multilevel policy approaches that improve COVID-19 vaccine knowledge, enhance trust, and address the complex interplay of sociocultural and structural barriers to vaccination. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Neubauer, Cajetan; Landecker, Hannah
A planetary health perspective on synthetic methionine Journal Article
In: The Lancet Planetary Health, vol. 5, no. 8, pp. e560–e569, 2021, ISSN: 2542-5196.
@article{Neubauer2021,
title = {A planetary health perspective on synthetic methionine},
author = {Cajetan Neubauer and Hannah Landecker},
doi = {10.1016/s2542-5196(21)00138-8},
issn = {2542-5196},
year = {2021},
date = {2021-08-00},
journal = {The Lancet Planetary Health},
volume = {5},
number = {8},
pages = {e560--e569},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Rensel, Michelle A.; Schlinger, Barney A.
11ß hydroxysteroid dehydrogenases regulate circulating glucocorticoids but not central gene expression Journal Article
In: General and Comparative Endocrinology, vol. 305, 2021, ISSN: 0016-6480.
@article{Rensel2021,
title = {11ß hydroxysteroid dehydrogenases regulate circulating glucocorticoids but not central gene expression},
author = {Michelle A. Rensel and Barney A. Schlinger},
doi = {10.1016/j.ygcen.2021.113734},
issn = {0016-6480},
year = {2021},
date = {2021-05-00},
journal = {General and Comparative Endocrinology},
volume = {305},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Goff, Anne Le; Allard, Patrick; Landecker, Hannah
Heritable changeability: Epimutation and the legacy of negative definition in epigenetic concepts Journal Article
In: Studies in History and Philosophy of Science Part A, vol. 86, pp. 35–46, 2021, ISSN: 0039-3681.
@article{LeGoff2021,
title = {Heritable changeability: Epimutation and the legacy of negative definition in epigenetic concepts},
author = {Anne Le Goff and Patrick Allard and Hannah Landecker},
doi = {10.1016/j.shpsa.2020.12.006},
issn = {0039-3681},
year = {2021},
date = {2021-04-00},
journal = {Studies in History and Philosophy of Science Part A},
volume = {86},
pages = {35--46},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
de Chadarevian, Soraya; Raffaetà, Roberta
COVID-19: Rethinking the nature of viruses Journal Article
In: HPLS, vol. 43, no. 1, 2021, ISSN: 1742-6316.
@article{deChadarevian2021,
title = {COVID-19: Rethinking the nature of viruses},
author = {Soraya de Chadarevian and Roberta Raffaetà},
doi = {10.1007/s40656-020-00361-8},
issn = {1742-6316},
year = {2021},
date = {2021-03-00},
journal = {HPLS},
volume = {43},
number = {1},
publisher = {Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Grote, Mathias; Onaga, Lisa; Creager, Angela N. H.; de Chadarevian, Soraya; Liu, Daniel; Surita, Gina; Tracy, Sarah E.
The molecular vista: current perspectives on molecules and life in the twentieth century Journal Article
In: HPLS, vol. 43, no. 1, 2021, ISSN: 1742-6316.
@article{Grote2021,
title = {The molecular vista: current perspectives on molecules and life in the twentieth century},
author = {Mathias Grote and Lisa Onaga and Angela N. H. Creager and Soraya de Chadarevian and Daniel Liu and Gina Surita and Sarah E. Tracy},
doi = {10.1007/s40656-020-00364-5},
issn = {1742-6316},
year = {2021},
date = {2021-03-00},
journal = {HPLS},
volume = {43},
number = {1},
publisher = {Springer Science and Business Media LLC},
abstract = {Abstract This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revitalized older issues, such as the relationship of life to matter, or of physicochemical inquiries to biology. This scholarship points to a novel molecular vista that opens up a pluralist view of molecularizations in the twentieth century and considers their relevance to current science. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Creager, Angela N. H.; Gaudillière, Jean-Paul (Ed.)
2021.
@{2021,
title = {RISK ON THE TABLE},
editor = {Angela N. H. Creager and Jean-Paul Gaudillière},
doi = {10.3167/9781789209440},
year = {2021},
date = {2021-01-01},
publisher = {Berghahn Books},
abstract = {Over the last century, the industrialization of agriculture and processing technologies have made food abundant and relatively inexpensive for much of the world’s population. Simultaneously, pesticides, nitrates, and other technological innovations intended to improve the food supply’s productivity and safety have generated new, often poorly understood risks for consumers and the environment. From the proliferation of synthetic additives to the threat posed by antibiotic-resistant bacteria, the chapters in Risk on the Table zero in on key historical cases in North America and Europe that illuminate the history of food safety, highlighting the powerful tensions that exists among scientific understandings of risk, policymakers’ decisions, and cultural notions of “pure” food. },
keywords = {},
pubstate = {published},
tppubtype = {}
}
2020
Vaughn, Rachel
On COVID-19: Food and/as Mutualism Journal Article
In: vol. 20, no. 3, pp. 108–110, 2020, ISSN: 1533-8622.
@article{Vaughn2020,
title = {On COVID-19: Food and/as Mutualism},
author = {Rachel Vaughn},
doi = {10.1525/gfc.2020.20.3.108},
issn = {1533-8622},
year = {2020},
date = {2020-08-01},
volume = {20},
number = {3},
pages = {108--110},
publisher = {University of California Press},
keywords = {},
pubstate = {published},
tppubtype = {article}
}