Scientists have devised a powerful new tool for understanding how DNA controls gene activity in cells. The tool allows researchers to map at high resolution, across large swaths of a cell’s genome, which DNA nucleotides work to regulate gene activity. “This is the first method that enables us to simultaneously test thousands of human DNA regulatory regions for their ability…
A new study by Johns Hopkins researchers suggests that a specialized area of the mosquito brain mixes tastes with smells to create unique and preferred flavors. The findings advance the possibility, they say, of identifying a substance that makes “human flavor” repulsive to the malaria-bearing species of the mosquitoes, so instead of feasting on us, they keep the disease to…
An international team of researchers has sequenced a strain of the Zika virus that will be used as a World Health Organization (WHO) reference strain to identify Zika virus infection in the blood, thus making it easier to diagnose the disease. While the reference material will undergo formal WHO review in October, the agency has given the go-ahead for the…
A genetic mutation may have helped modern humans adapt to smoke exposure from fires and perhaps sparked an evolutionary advantage over their archaic competitors, including Neandertals, according to a team of researchers. Modern humans are the only primates that carry this genetic mutation that potentially increased tolerance to toxic materials produced by fires for cooking, protection and heating, said Gary…
A comprehensive investigation of the underlying genetic architecture of type 2 diabetes has unveiled the most detailed look at the genetic differences that heighten a person’s risk for disease development. The findings, published today in the journal Nature by an international team of more than 300 scientists led by the University of Oxford, the Broad Institute, and the University of…
Monkeys infected with Zika virus are protected from future infection, and pregnancy dramatically prolongs infection in monkeys, findings that could help in fighting the virus in people, UW-Madison researchers said Tuesday. Scientists on campus have infected 13 rhesus macaque monkeys with Zika, a virus that has caused an outbreak involving severe birth defects such as brain damage in Latin America…