MIT scientists report the use of a CRISPR methodology to cure mice of a rare liver disorder caused by a single genetic mutation. They say their study (“Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype”), published in Nature Biotechnology, offers the first evidence that this gene-editing technique can reverse disease symptoms in living animals. CRISPR, which provides a…
One in a thousand children in the United States is deaf, and one in three adults will experience significant hearing loss after the age of 65. Whether the result of genetic or environmental factors, hearing loss costs billions of dollars in healthcare expenses every year, making the search for a cure critical. Now a team of researchers led by Karen…
Keeping track of what we reveal about ourselves each day—through email and text messages, Amazon purchases and Facebook “likes”—is hard enough. Imagine a future when Big Data has access not only to your shopping habits, but also to your DNA and other deeply personal data collected about our bodies and behavior—and about the inner workings of our proteins and cells.…
“Where do new genes come from?” is a long-standing question in genetics and evolutionary biology. A new study from researchers at the University of California, Davis, published Jan. 23 in Science Express, shows that new genes are created from non-coding DNA more rapidly than expected. “This shows very clearly that genes are being born from ancestral sequences all the time,”…
Professor of Genetics Scott Williams, PhD, of the Institute for Quantitative Biomedical Sciences (iQBS) at Dartmouth’s Geisel School of Medicine, has made two novel discoveries: first, a person can have several DNA mutations in parts of their body, with their original DNA in the rest—resulting in several different genotypes in one individual—and second, some of the same genetic mutations occur…
Researchers from Nanjing Normal University and BGI report their original genomic research on Baiji, also known as Yangtze River dolphin (Lipotes vexillifer). The study gives new insight into the genetic and evolutionary adaptations of Dolphin, and provides valuable resources for the conservation of mammals and cetaceans in particular. The latest study was published online in the journal Nature Communications. Nicknamed…