genetics

Humans Still Evolving, Large-Scale Study of Genetic Data Shows

In a study analyzing the genomes of 210,000 people in the United States and Britain, researchers have found that the genetic variants linked to Alzheimer’s disease and heavy smoking are less frequent in people with longer lifespans, suggesting that natural selection is weeding out these unfavorable variants in both populations. “It’s a subtle signal, but we find genetic evidence that…

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Study Reveals White Nationalists’ Reactions When Genetics Test Results Challenge Their Identity

A new study by UCLA researchers reveals the range of reactions — from rejection to reinterpretation to acceptance — after white nationalists learn that DNA ancestry test results indicate they may not be as white or European as they previously thought. The study, “When Genetics Challenges a Racist’s Identity: Genetic Ancestry Testing Among White Nationalists,” is the work of UCLA researchers Aaron Panofsky and…

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How The Genome Sets its Functional Micro-Architecture

The genes that are involved in the development of the fetus are activated in different tissues and at different times. Their expression is carefully regulated by so-called “enhancer sequences”, which are often located far from their target genes, and requires the DNA molecule to loop around and bring them in close proximity to their target genes. Such 3D changes of…

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First Big Efforts to Sequence Ancient African DNA Reveal How Early Humans Swept Across the Continent

The study of ancient human DNA has not been an equal opportunity endeavor. Early Europeans and Asians have had portions of their genomes sequenced by the hundreds over the past decade, rewriting Eurasian history in the process. But because genetic material decays rapidly in warm, moist climates, scientists had sequenced the DNA of just one ancient African. Until now. This week,…

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Racism Aggravates Treatment-Resistant Asthma

Racial discrimination experienced by African-American children and young adults exacerbates a type of asthma known to be resistant to standard treatment, according to a study headed by researchers at UC San Francisco. The 576 study participants, who were African-Americans with asthma, aged between 8 and 21, were asked if they had been hassled, made to feel inferior or prevented from…

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