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Western Lowland Gorilla Genome Mapped with New Level of Accuracy

GorillaThe genome of the Western lowland gorilla (Gorilla gorilla ssp. gorilla) has been sequenced at a high level of quality beginning to approach that of the human genome, says a team of scientists led by Prof. Evan Eichler from the University of Washington. Prof. Eichler and his colleagues used long-read sequencing technology, along with a unique combination of algorithms, to reconstruct a much more accurate genome, using DNA isolated from a Western lowland gorilla named Susie at the Lincoln Park Zoo in Chicago. “The genome assembly that results from using the long-read data provides a more complete picture of gene content, structural variation and repeat biology, as well as allows us to refine population genetic and evolutionary inferences.” These results provide a better understanding of genetic variation between our species and our non-human cousins, but also demonstrate ways to sequence other mammalian genomes with better accuracy.

The results were published in the April 1, 2016 issue of the journal Science.

Read the full article here.

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